Antagonist profile of Apis mellifera 5-HT2 receptors.
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IC50 values (potency) and relative efficacy were calculated from concentration-response curves for each drug. Efficacy is given as the maximal inhibition (%) of fluorescence compared with 50 nM serotonin in the absence of antagonist and calculated by curve fitting. Values are means of the results of two independent experiments, each performed in octuplicates.
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2015-12-02
