Depletion of CD4 T Cells Does Not Equalize Spinal Cord Titers of 27 gfp Compared to 27US11 or 27m152, Whereas Depletion of CD8 T Cells Does
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https://figshare.com/articles/dataset/Inhibition_of_MHC_Class_I_Is_a_Virulence_Factor_in_Herpes_Simplex_Virus_Infection_of_Mice/153122
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BALB/c mice were either (A) untreated; or (B) and (C) treated 3 and 2 days before the time of infection with 200 μg α-CD4 MAb (GK1.5) or α-CD8 MAb (53–6.7), respectively. Mice were infected with 2.5 × 105 pfu of 27 gfp, 27US11, or 27m152 on day 0, and footpads and spinal cord were harvested on day 6. This experiment was distinct from the experiments shown in Figures 6 and 7, but the findings for A and C are similar to those shown in Figures 6A and 7C, respectively. (357 KB EPS)
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2015-12-02
