Amount of substrates consumed and products formed per gram biomass during mid-exponential growth in shake flask or in controlled fermentor setting.

Data presented are yield data averaged over 2�C4 independent experiments during growth between an OD600 of 0.2 and 0.7. Yield data are in mmol gDW?1. Negative values indicate uptake of the compound. The last two columns indicate the constraints used for the robustness analysis of Figure 3. Other constraints can be found in Dataset S1.ND not determined; LB lower bound; UB upper bound.aPresented unit is in mmol gDW?1 for comparison to measured fluxes. To get to flux constraints with unit mmol h?1 gDW?1 (as presented in Dataset S1) multiply with the growth rate (0.26 h?1).