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p53-dependent transcription program in HepG2 cells
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创建时间：
2012-03-30
相关数据集
Chen et al 2019 "iASPP mediates p53 selectivity through a modular mechanism fine-tuning DNA recognition"
Raw Western blot and luciferase assay data to support the experimental results presented in the publication by Chen et al 2019 entitled "iASPP mediates p53 selectivity through a modular mechanism fine
NIAID Data Ecosystem90
Gene expression in human lymphoblastoid cell-line GM12878 in response to doxorubicin treatment. Homo sapiens
To determine if induced p53 binding is associated with gene expression in genome-wide. We examined mRNA levels with the Affymetrix Human Exon 1.0 ST platform in human lymphoblastoid GM12878 cells trea
NIAID Data Ecosystem40
p53 Recruitment of CREB Binding Protein Mediated through Phosphorylated CREB: a Novel Pathway of Tumor Suppressor Regulation
CREB binding protein (CBP) is a 270-kDa nuclear protein required for activated transcription of a large number of cellular genes. Although CBP was originally discovered through its interaction with ph
PubMed Central30
Global analysis of p53-regulated transcription reveals its direct targets and unexpected regulatory mechanisms (GRO-Seq). Homo sapiens
GRO-seq of HCT116 cells treated with Nutlin to activate p53 Overall design: HCT116 cells were treated with Nutlin or DMSO for 1 hour
NIAID Data Ecosystem40
Genomewide analysis of the human p53 transcriptional network unveils a lncRNA tumor suppressor signature (expression)
We report the application of high-throughput sequencing to performed the p53 regulated trancriptome in HCT116 colon cancer cells treated with the DNA damage 5FU. To study the direct targets of p53 we
NIAID Data Ecosystem30
