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Oxidative stress induces mitochondrial dysfunction and a protective unfolded protein response in RPE cells

ChEBI2014-01-30 更新2026-07-21 收录

视网膜色素上皮细胞研究

线粒体功能障碍

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-49107 数据链接链接失效反馈

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Oxidative stress induces mitochondrial dysfunction and a protective unfolded protein response in RPE cells

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2014-01-30

突触调控异常

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Maternal immune activation (MIA) is a risk factor for neurodevelopmental disorders in offspring, but the pathomechanism is largely unknown. The aim of our study was to analyse the molecular mechanisms

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Figure 2 and Extended data Figure 2

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Raw data for Figure 2 and extended data from the manuscript " Ubiquinone deficiency drives reverse electron transport to disrupt hepatic metabolic homeostasis in obesity."

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Mitochondrial and extramitochondrial apoptotic signaling pathways in cerebrocortical neurons

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In cultured cerebrocortical neurons, mild excitotoxic insults or staurosporine result in apoptosis. We show here that N-methyl-d-aspartate (NMDA) receptor-mediated, but not staurosporine-mediated, apo

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The Yeast Complex I Equivalent NADH Dehydrogenase Rescues pink1 Mutants

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Pink1 is a mitochondrial kinase involved in Parkinson's disease, and loss of Pink1 function affects mitochondrial morphology via a pathway involving Parkin and components of the mitochondrial remodeli

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Single -cell transcriptomic profiling of stem cell derived retinal pigment epithelial cell monolayers after subretinal transplantation

视网膜色素上皮细胞研究

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Transplantation of stem cell derived retinal pigment epithelial (RPE) cells can potentially restore vision in patients with age-related macular degeneration (AMD). Several landmark Phase I/II clinical

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Oxidative stress induces mitochondrial dysfunction and a protective unfolded protein response in RPE cells

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