Safety outcomes.

NIAID Data Ecosystem2026-03-09 收录

药物性肝损伤防治

肝功能异常不良事件

数据链接：

https://figshare.com/articles/dataset/_Safety_outcomes_/1255385 数据链接链接失效反馈

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资源简介：

aBoth TEAEs considered treatment-related were severe abnormal liver function tests, which were considered AESIs. bDetermined by Chi-squared test. Safety outcomes.

创建时间：

2014-12-01

Odds Ratios (ORs) for MNLIHD between Amiodarone and non- Amiodarone group.

药物性肝损伤防治

胺碘酮安全性

†Adjusted for statins, anti-diabetics, NSAIDS, antiarrhythmic drugs of propafenone, quinidine, comorbidities of diabetes, chronic liver disease, cirrhosis, HBV infection, HCV infection, and alcoholism

NIAID Data Ecosystem50

3`mRNA sequencing of liver RNA (MACE) at the 30h time point after acetaminophen (APAP) 300mg/kg administration

药物性肝损伤防治

基因表达谱分析

Hepatic RNA from mice (C57BL/6) of 2 groups (APAP-treated (300mg/kg), n=8; APAP (300mg/kg)-AZD7986 (5mg/kg), n=8) were pooled at equal shares. Thereafter, pooled RNA underwent analysis by 3`mRNA seque

NIAID Data Ecosystem20

Single cell RNA sequencing on the early hepatic transcriptomic landscape

药物性肝损伤防治

单细胞转录组学

Single cell RNA sequencing, spatial reconstruction of the liver lobule after acetaminophen (300 mg/kg) Hepatocytes were isolated from either control or APAP-treated mice (2h) and underwent 10x Chromiu

NIAID Data Ecosystem10

Supplementary Material for: Reparation of Isoniazid and Rifampicin Combinatorial Therapy-Induced Hepatotoxic Effects by Bacopa monnieri

药物性肝损伤防治

受体相互作用

Drug-induced liver injury is a major challenge in treating tuberculosis with isoniazid (INH) and rifampicin (RIF). This study was aimed at evaluating the protective effects of Bacopamonnieri (Brahmi)

NIAID Data Ecosystem20

Body, relative liver and kidney weights and AST and ALT levels in the blood serum of rats treated with DEN or vehicle (saline) and administered Valerian at doses of 50, 500 and 5000 ppm.

药物性肝损伤防治

毒性评估

Data are Mean ± SD; aP<0.05; bP<0.01; cP<0.0001 vs DEN control group d(n = 10) for DEN, DEN→Val, 50 ppm, DEN→Val, 500 ppm, DEN→Val, 5000 ppm, Vehicle→Val,5000 ppm groups and (n = 9) for Vehicle contro

NIAID Data Ecosystem10

Safety outcomes.

资源简介：

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