Morphometry of smooth muscle cell nuclei of the tunica media of GSV.

(A) Representative cross-section of a GSV. Smooth muscle cell compartment is visualized by smooth muscle actin staining. (B, C) Morphometry was conducted on HE stained slides (using Zeiss Axiovision). Statistical analysis of nuclear measurements of paired healthy (D) and varicose (E) GSV specimens demonstrating no significant difference of nuclear size in varicose GSV compared to healthy GSV.