Crystal Structure of ANV419, a novel IL-2/anti-IL-2 antibody fusion protein

Crystal Structure of ANV419, a novel IL-2/anti-IL-2 antibody fusion protein Descriptor: ANV419 heavy-chain, ANV419 light-chain Authors: Rondeau, J.M, Wirth, E. Deposit date: 2024-02-08 Release date: 2024-07-31 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Discovery and development of ANV419, an IL-2/anti-IL-2 antibody fusion protein with potent CD8+ T and natural killer cell-stimulating capacity for cancer immunotherapy. Mabs, 16, 2024ANV419晶体结构：一种新型白细胞介素2（Interleukin-2, IL-2）/抗IL-2抗体融合蛋白 描述项：ANV419重链、ANV419轻链 作者：Rondeau J.M.、Wirth E. 沉积日期：2024-02-08 发布日期：2024-07-31 最后修改日期：2024-10-16 检测方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.05埃（Å） 引用文献：《用于癌症免疫治疗、具备强效CD8阳性T细胞与自然杀伤细胞刺激能力的IL-2/抗IL-2抗体融合蛋白ANV419的发现与开发》，发表于《单克隆抗体》（Mabs）2024年第16卷。