Post-operative delirium (POD) is a serious complication which occurs after surgery, especially in the elderly undergoing total hip replacement surgery. Gut microbiota has been recognized to infuence b
Background: Little is known about the underlying mechanisms of the similarities in the core features of postoperative delirium (POD) and α-synuclein (α-syn)-related cognitive disorders. We herein inve
Demographic, anesthetic, and surgical information of all patients were documented to detect any statistical difference between the preparation and non-preparation group.
At the animal level, a rat model of postoperative delirium was constructed by deep anesthesia and treated intraperitoneally and respectively with low, medium, and high doses of melatonin. The behavior
