Complete H5N5 Influenza A Virus Genomes: Codon Adaptation and Metadata

This dataset includes 446 complete H5N5 influenza A virus sequences from NCBI, processed via local bioinformatics pipelines.
Sequences were filtered, aligned with MAFFT (--auto), and trimmed. Codon usage metrics (ENc, CAI for human/avian hosts, GC3, RSCU, CPB, PR2) were computed per sequence. Year and country metadata were parsed from headers. Package contains aligned FASTA, codon metrics CSV, QC summaries, and visualizations.

CODON USAGE SUMMARY: H5N5
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Total sequences: 446
Valid CDS: 48 (10.8%)
Valid CAI: 48 (10.8%)

METRIC STATISTICS (Mean ± SD):
ENc (Effective Number of Codons): 35.114 ± 2.216
CPB (Codon Pair Bias): 4.912 ± 0.897
CAI_human: 3.419 ± 0.116
CAI_avian: 3.438 ± 0.119
GC3: 0.446 ± 0.035
PR2_A (A3/(A3+T3)): 0.576 ± 0.044
PR2_G (G3/(G3+C3)): 0.528 ± 0.041

INTERPRETATION:
→ Strong codon usage bias (ENc < 40)
→ Similar adaptation to human/avian hosts

Data processed by: [e-mail]