Nonalcoholic fatty liver disease (NAFLD), which is the most common liver disease, is associated with type 2 diabetes mellitus and metabolic syndrome. Although there is no consensus on the treatment of
Data presented as mean ± SEM. ALT, alanine aminotransferase; AST, aspartate aminotransferase, BMI, body mass index; SS, simple steatosis; NASH, nonalcoholic steatohepatitis. aP<0.01 vs. SS; bP<0.01 vs
Glutaredoxin-1 (Glrx) controls redox signaling and has an anti-apoptotic function. We evaluated the role of Glrx on hepatic cell damage and fibrosis induced by a high-fat diet. We fed mice a high-fat
Non-alcoholic steatohepatitis (NASH) represents a major economic burden and is characterized by triglyceride accumulation, inflammation, and fibrosis. No pharmacological agents are currently approved
