The use of computational modeling algorithms to guide the design of novel enzyme catalysts is a rapidly growing field. Force-field based methods have now been used to engineer both enzyme specificity
Table 1 Kinetic parameters of P. crispum SDH. V max - maximal reaction rate of enzyme reaction, K - Michaelis constant of the specific substrate, K ′ -apparent m m Michaelis constant at a given concen
The use of computational modeling algorithms to guide the design of novel enzyme catalysts is a rapidly growing field. Force-field based methods have now been used to engineer both enzyme specificity