Highly Enantioselective Synthesis of Polysubstituted Tetrahydroquinolines <i>via</i> Organocatalytic Michael/Aza-Henry Tandem Reactions
收藏NIAID Data Ecosystem2026-03-07 收录
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Highly enantioselective chiral bifunctional thiourea catalyzed asymmetric tandem reactions for synthesis of substituted tetrahydroquinolines are described. Substituted tetrahydroquinolines were given in good yields (up to 98%), high enantioselectivities (up to >99% ee), and diastereoselectivities (up to 20:1 dr).
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2011-03-04
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