Frequency of CS-specific CD4+ T cells expressing at least 2 cytokines/activation markers per million PBMC, by treatment group and protection status (ATP cohort for immunogenicity).

ARR = first dose with Ad35.CS, and the second and third doses with RTS,S/AS01B RRR = three doses with RTS,S/AS01B P values calculated using log-transformed cell frequency per million PBMC in Students t-test NP = non-protected; P = protected Frequency of CS-specific CD4+ T cells expressing at least 2 cytokines/activation markers per million PBMC, by treatment group and protection status (ATP cohort for immunogenicity).