Table summarizes the specific enrichment of HsOrc2 and HsMcm7 at oriP and the integration site shown in the histograms in Figure 3.

The average enrichment at oriP and the integration site are normalized in relation to the reference site. Three independent experiments are shown for the three cell cycle fractions analyzed. For location of the PCR primer pairs see Figure 2. Because DS does not exhibit cell cycle-dependent binding of HsOrc2, the mean value and standard deviation of the fragments was used to establish the average enrichment (average). The mean value at the reference site, which represents the non-sequence specific DNA-binding activity of the analyzed protein, was determined and used for normalization to calculate the accumulation for oriP and the integration site. The obtained numbers represent the enrichment at the particular fragment above the reference site level. With the exception of ΔDS(p2910), the enrichment of HsMcm7 is cell cycle-dependent (cell cycle). Therefore no average value was determined.