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Additional file 2 of Genome-wide association and integrative analyses of relative handgrip strength identify polygenic determinants of gastrointestinal disorder susceptibility

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NIAID Data Ecosystem2026-05-10 收录
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https://figshare.com/articles/dataset/Additional_file_2_of_Genome-wide_association_and_integrative_analyses_of_relative_handgrip_strength_identify_polygenic_determinants_of_gastrointestinal_disorder_susceptibility/31367301
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Supplementary Material 2: Supplementary table 1. ICD9 and ICD10 codes of diseases in the study. Supplementary table 2. Genomic risk loci table from FUMA. Supplementary table 3. Independent significant SNPs. Supplementary table 4. Lead SNP table. Supplementary table 5. Mapped gene tables (from FUMA). Supplementary table 6. ANNOVAR results. Supplementary table 7. Enrichment analysis using rGreat. Supplementary table 8. Enrichment analysis using gprofiler. Supplementary table 9. Tissue specificity analyses using deTS. Supplementary table 10. Colocalization. Supplementary table 11. TWAS (PrediXcan) results in the skeletal muscle. Supplementary table 12. TWAS (JTI) results in the skeletal muscle. Supplementary table 13. FOCUS credible genes (PIP > 0.9). Supplementary table 14. LDSC genetic correlation. Supplementary table 15. Mendelian randomization using inverse variance weighted (IVW) method. Supplementary table 16. Mendelian randomization using weighted median method. Supplementary table 17. Mendelian randomization using MR-Egger method. Supplementary table 18. Pleiotropic analyses in Mendelian randomization. Supplementary table 19. Heterogeneity analyses in Mendelian randomization. Supplementary table 20. Logistic regression of RHGS PRS on the disease risks. Supplementary table 21. Cox regression of RHGS PRS on the disease risks. Supplementary table 22. Logistic regression of RHGS measures on the disease risks. Supplementary table 23. Cox regression of RHGS measure on the disease risks. Supplementary table 24. Logistic regression of RHGS measures on the disease risks in the rest of 30% population. Supplementary table 25. Cox regression of RHGS measures on the disease risks in the rest of 30% population.
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2026-01-27
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