Identification of a New Zinc Binding Chemotype by Fragment Screening

Identification of a New Zinc Binding Chemotype by Fragment Screening Descriptor: (5R)-5-[(2,4-dimethoxyphenyl)methyl]-1,3-thiazolidine-2,4-dione, 1,2-ETHANEDIOL, Carbonic anhydrase 2, ... Authors: Peat, T.S, Poulsen, S.A, Ren, B, Dolezal, O, Woods, L.A, Mujumdar, P, Chrysanthopoulos, P.K. Deposit date: 2016-11-23 Release date: 2017-08-30 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Identification of a New Zinc Binding Chemotype by Fragment Screening. J. Med. Chem., 60, 2017通过片段筛选鉴定新型锌结合化学型 描述项：(5R)-5-[(2,4-二甲氧基苯基)甲基]-1,3-噻唑烷-2,4-二酮、1,2-乙二醇、碳酸酐酶2（Carbonic anhydrase 2），…… 作者：Peat, T.S、Poulsen, S.A、Ren, B、Dolezal, O、Woods, L.A、Mujumdar, P、Chrysanthopoulos, P.K. 入库日期：2016-11-23 发布日期：2017-08-30 最后修改日期：2023-10-04 实验方法：X射线衍射（X-RAY DIFFRACTION，1.54 Å） 引用：《通过片段筛选鉴定新型锌结合化学型》. 《药物化学杂志（J. Med. Chem.）》, 第60卷, 2017