SoCal Kinesia and Incentivization for Parkinson's Disease (SKIP): Approach-Avoid

# Approach-Avoid Task (approachavoid) from the SKIP Dataset

The Socal Kinesia and Incentivization for Parkinson's Disease (SKIP) dataset facilitates research across human sciences, focusing on human movement and the modulatory impact of incentivization, specifically in the context of Parkinson's Disease (PD).

SKIP so far contains three task-based fMRI datasets and one resting-state fMRI dataset.

### This dataset: Approach-Avoid Task (approachavoid)
- **Description:** 78 participants making time-constrained reaches toward or away from emotional images.
- Valence (Positive and Negative) of pictures and joystick movement direction (Approach and Avoid) were manipulated.
- Participants pulled the joystick towards themselves (approach) or away from themselves (avoid) based on the picture's valence.
- Task design creates emotion-action congruent (Positive-Approach, Negative-Avoid) and incongruent (Positive-Avoid, Negative-Approach) conditions.

**Current Version:** 1.0.1
**Note:** This version contains data from healthy controls only. Future updates will include data from PD patients and a broader range of assays in both healthy controls and PD subjects, such as cardiac-autonomic and pupillometry data.

Our goal for SKIP is to become the leading global resource as the world advances in its capacity for powerful and innovative analyses, allowing researchers free access to comprehensive physiological and behavioral assays of movement, and how incentives influence them, in the context of PD.

## Funding
SKIP was funded in whole by Aligning Science Across Parkinson's ASAP-020-519 through the Michael J. Fox Foundation for Parkinson's Research (MJFF).

## More Information
For more information, please visit:
- [SKIP Official Website](http://www.socalkinesia.org)
- [Aligning Science Across Parkinson's (ASAP)](https://parkinsonsroadmap.org/#)

## Citation
Please cite the following:
Dundon, N. M., Rizor, E., Stasiak, J., Wang, J., Sabugo, K., Villaneuva, C., Barandon, P., Bostan, A. C., Lapate, R. C., & Grafton, S. T. (2024). Dissociation of novel open loop from ventral putamen to motor areas from classic closed loop in humans II: task-based function. bioRxiv, 2024-06.

## other fMRI Tasks part of SKIP

### Incentivized Reaching Task (incenreach)
- **Description:** 68 participants performing time-constrained precision reaches to spatial targets in different monetary incentive contexts.
- Trials were categorized into "standard" (80%) and "high incentive" (20%) trials.
- High incentive trials could either obtain a large reward (jackpot) or avoid a large loss (robber).
- Task design compares positive and negative incentive valence.

### Active Escape Task (activeescape)
- **Description:** 69 participants tracking an 18-second countdown and making time-sensitive motor responses under the threat of electric shock.
- Shock intensity (mild vs unpleasant) and controllability were manipulated.
- In "controllable" trials, participants could avoid shocks if motor responses were fast enough.
- In "uncontrollable" trials, a shock was always received.
- Task design creates controllable-mild, uncontrollable-mild, controllable-unpleasant, and uncontrollable-unpleasant conditions.

### Ultra-High Field Functional Connectivity / Network Mapping (highresFC)
- **Description:** 21 participants undergoing ultra-high field (7T) multi-echo scans at rest.
- Multi-echo imaging was used to reduce non-BOLD signals.
- Ultra-high field imaging provides greater image resolution and reliability of functional connectivity network analyses.
- Ideal for mapping network properties of small, deep subcortical nuclei, such as those in the basal ganglia.