Mechanistic study of Wee1 kinase inhibition with AZD1775 exposes drug targetable vulnerabilities in acute B-lymphoblastic leukemia [scATAC-seq]
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https://www.ncbi.nlm.nih.gov/sra/SRP409881
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资源简介：
This study characterized the effect of WEE1 kinase inhibition using AZD1775 treatment on single-cell accessible chromatin and gene expression profile in the acute lymphoblastic leukemia cell line RS4;11 that represents the KMT2A-rearranged subtype. Overall design: scATAC-seq samples were generated from 24 h after AZD1775 (Wee1i) using the 10x Genomics Chromium platform and protocols. DMSO treated cells were used as controls. Parallel cell cultures were processed for scRNA-seq.
创建时间：
2024-06-27
