MeOTf-Mediated Annulation of Alkylnitriles and Arylalkynes Leading to Polysubstituted NH‑Pyrroles
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资源简介：
A metal-free multicomponent domino reaction for the highly regioselective synthesis of tetrasubstituted NH-pyrroles from readily available alkylnitriles, arylalkynes, and MeOTf has been developed. A variety of NH-pyrroles were obtained in moderate to good yields under mild conditions. In addition, the reactions using diarylalkynes with electron-rich aryl groups were found to afford isoquinolines.
创建时间：
2018-03-27
