Human Ageing Genomic Resources
收藏资源简介:
The Human Ageing Genomic Resources (HAGR) is a collection of databases and tools for the biology and genetics of ageing. HAGR features several databases with high-quality, manually-curated data: 1) GenAge, a database of genes associated with ageing in humans and model organisms; 2) AnAge, an extensive collection of longevity records and complementary traits for over 4,000 vertebrate species; and 3) GenDR, a database containing both gene mutations that interfere with dietary restriction-mediated lifespan extension and consistent gene expression changes induced by dietary restriction.
人类衰老基因组资源库(Human Ageing Genomic Resources, 简称HAGR)是一套面向衰老生物学与遗传学的数据库与工具集合。HAGR下设多个经人工精心整理的高质量数据库,具体如下:1)GenAge数据库:收录人类及模式生物中与衰老相关的基因;2)AnAge数据库:涵盖超过4000个脊椎动物物种的寿命记录及配套补充性状的大规模数据集;3)GenDR数据库:收录两类数据,其一为可干扰饮食限制介导的寿命延长效应的基因突变,其二为饮食限制诱导的一致性基因表达变化。




