Mesenchymal Stem Cells Generated from Human Urine-derived iPSCs Exhibit Low Immunogenicity and Im-munomodulatory Profile

We conducted transcriptome analysis to determine the differences between umbilical cord-derived mesenchymal stem cells (named UCMSC) and iMSCs generated from human urine-derived iPSC (named B6MSC) at the transcriptomic level. The expression of genes related to aging, rejuvenation, proliferation or immune regulatory factors in iMSCs was different significantly from that of UCMSCs. Comparative gene expression profiling analysis of RNA-seq data for UCMSCs and iMSCs generated from human urine-drived iPSC.