CRAC of yeast RNA polymerase II in WT and isw1Δ cells in standard conditions or upon ER stress.

We obtained RNA polymerase II occupancy profile across the genome of WT and isw1Δ Saccharomyces cerevisiae strains grown under normal conditions or after ER stress induction for 2H with1 µg/mL tunicamycin (Tm).本研究获取了野生型（Wild Type，WT）与isw1缺失突变（isw1Δ）酿酒酵母（Saccharomyces cerevisiae）菌株在正常培养条件下，以及经1 μg/mL衣霉素（tunicamycin，Tm）诱导内质网应激2小时后的全基因组RNA聚合酶II（RNA polymerase II）结合占据谱。