Imaging mass cytometry data- OXPHOS complex profiling
收藏data.ncl.ac.uk2021-03-03 更新2025-01-09 收录
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https://data.ncl.ac.uk/articles/dataset/Imaging_mass_cytometry_data-_OXPHOS_complex_profiling/14079497/1
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This dataset contains the original log data generated from imaging mass cytometry on a cohort of post-mortem human midbrain section. This dataset were used to perform the profiling of the expression level of mitochondrial OXPHOS proteins. The cohort included idiopathic PD cases (n=9) and POLG cases (n=4), alongside individuals without neurological disease used as controls (n=10). The use of tissue sections adhered to the Medical Research Council’s (MRC) guidelines on the use of human tissue in medical research. The manuscript of this work is currently under minor correction with npj Parkinson's Disease (#NPJPARKD-00529).
本数据集包含了源自对尸检人脑中脑切片进行成像质谱计检测所生成的原始日志数据。该数据集被用于对线粒体氧化磷酸化蛋白表达水平的进行剖析。研究队列包括9例特发性帕金森病病例(n=9)和4例POLG病例,以及作为对照的无神经疾病个体(n=10)。组织切片的使用遵循了医学研究理事会(MRC)关于在医学研究中使用人类组织的相关指南。本研究的论文目前正处于细微修订阶段,发表在《npj帕金森病》(#NPJPARKD-00529)上。
提供机构:
Newcastle University



