Goat Scrapie Algeria

Goats are adapted to live in harsh areas of the world ensuring minimum levels of milk and meat production without much economic input. Scrapie is a fatal prion disease of small ruminants detected in different countries worldwide. Polymorphisms in the prion protein gene (PRNP) modify the degree of susceptibility/resistance to scrapie. PRNP polymorphisms were analysed in the four main Algerian goat breeds (Naine de Kabylie, Arbia, Mozabite, Mekatia), and in two native breeds of South Italy (Aspromontana from Calabria and Cilentana from Campania).山羊可适应全球各类严苛生境，仅需极低经济投入即可维持基础水平的乳肉产出。痒病（Scrapie）是一种致死性小反刍动物朊病毒病，目前已在全球多个国家被检出。朊蛋白基因（prion protein gene, PRNP）的多态性可调控宿主对痒病的易感性与抗性水平。本研究对阿尔及利亚四大主养山羊品种（卡比利亚奈恩羊（Naine de Kabylie）、阿尔比亚羊（Arbia）、莫扎比特羊（Mozabite）、梅卡蒂亚羊（Mekatia）），以及意大利南部的两个本土山羊品种（来自卡拉布里亚的阿斯普罗蒙塔纳羊（Aspromontana）与来自坎帕尼亚的奇伦塔纳羊（Cilentana））的PRNP多态性进行了分析。