Caesarean section association with chronic immune disorders

In developed countries, the rate of caesarean births has increase 50% over the last decade and is estimated to continue increasing, on average 1 in 3 births are preformed caesarean delivery.). In recent years, concerns and questions have arisen on the potential long term consequences for infant health born from CD (4). Parallel with the rise of CD, there has been an escalation in doctor diagnosed allergic diseases. The frequencies of allergies are increasing in prevalence in countries around the world (specifically western countries) and has no specific identification of a source (5-6).One of the predominate theories explaining the correlation between CD and higher rates of asthma, obesity, allergens during childhood is the hygiene hypothesis, insinuating that the introduction and growth of microbial flora in the intestines during prenatal and postnatal development correlates to faster developing immune system which decrease probability of developing allergic diseases. Studies were found using multiple databases; Web of Science, Scopus and Plos one listed from 1976 to 2015. Most, 80%, of the studies were found on web of Science and Plos one while Scopus had many studies that were not specific enough for this review and were excluded. The terms used to specify the search terms on each database were caesarean section OR c-section OR mode of delivery OR pregnancy complications as the primary topic with subtopic including immune function OR chronic Immune disorder, allergy OR allergic OR food allergy OR food intolerance OR asthma OR atopy, and gut macrobiotic. The topics were combined in different ways to achieve a broad but specified number of studies. To be approved, the abstract, introduction and methods were read on the basis of if their research considered caesarean sections as the main factor and studied the potential outcome of caesarean sections or pregnancy complications resulting in a caesarean sections and if the infants from those caesarean sections developed any chronic disorders