Correlations* and effect estimates (β) † between total urinary arsenic (As), DNA methylation and gene expression in Argentina, as well as the influence of haplotype on gene expression.
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A. denotes CpG sites that were positively associated with the AS3MT haplotype and B. denotes CpG sites that were inversely associated with the haplotype.*rs and p-value from Spearman correlation.†β and p-value from multivariable regression.‡Model (the β stated in the table is β1): Gene expression = α+β1× total urinary arsenic (natural ln transformed)+β2× RIN.§Model (the β stated in the table is β1): Gene expression = α+β1×copies of AS3MT haplotype+β2× total urinary arsenic (natural ln transformed)+β3×RIN.¶Model (the β stated in the table is β1): Gene expression = α+β1×methylation level+β2× total urinary arsenic (natural ln transformed)+β3×RIN.
创建时间：
2015-12-02
