Joint X-ray/neutron structure of Thermus thermophilus serine hydroxymethyltransferase (TthSHMT) in internal aldimine state with L-Ser bound in a pre-Michalis complex

Joint X-ray/neutron structure of Thermus thermophilus serine hydroxymethyltransferase (TthSHMT) in internal aldimine state with L-Ser bound in a pre-Michalis complex Descriptor: SERINE, SULFATE ION, Serine hydroxymethyltransferase Authors: Drago, V.N, Kovalevsky, A. Deposit date: 2023-05-12 Release date: 2023-08-16 Last modified: 2023-11-15 Method: NEUTRON DIFFRACTION (2.3 Å), X-RAY DIFFRACTION Cite: Revealing protonation states and tracking substrate in serine hydroxymethyltransferase with room-temperature X-ray and neutron crystallography. Commun Chem, 6, 2023嗜热栖热菌（Thermus thermophilus）丝氨酸羟甲基转移酶（serine hydroxymethyltransferase，缩写TthSHMT）处于内部醛亚胺状态且结合有米氏复合物前体形式L-丝氨酸（L-Ser）的联合X射线/中子晶体结构 描述项：丝氨酸（SERINE）、硫酸根离子（SULFATE ION）、丝氨酸羟甲基转移酶（Serine hydroxymethyltransferase） 作者：Drago, V.N.、Kovalevsky, A. 存档日期：2023-05-12 发布日期：2023-08-16 最后修改日期：2023-11-15 实验方法：中子衍射（NEUTRON DIFFRACTION，2.3 Å）、X射线衍射（X-RAY DIFFRACTION） 引用文献：利用室温X射线与中子晶体学解析丝氨酸羟甲基转移酶的质子化状态并追踪底物，《Commun Chem》，6卷，2023年