Data from the CRISPR library screen enabled us to isolate the target protein in this research. Using live-cell imaging, we were able to validate the involvement of the hits from the CRISPR library scr
We characterize genetic determinants of human cardiomyocyte polypolidization and CCNB1 insufficiency using pooled CRISPR screen methods CCNB1-GFP iPSCs were transduced with lentiviral Cas9 and librari
data used to create main figures for: Park et. al., Efficient prioritization of CRISPR screen hits by accounting for targeting efficiency of guide RNA, BMC Biol, 2023.
Immunologic memory is one of the hallmarks of the successful future defense of a host against pathogenic insults and cancer. The formation of memory T cells is characterized by distinct changes in T c
