Arabidobsis ATR7 2020 RNAseq

Zenodo2020-12-21 更新2026-04-07 收录

植物环境胁迫响应

拟南芥基因功能分析

数据链接：

https://zenodo.org/record/4382237 数据链接链接失效反馈

官方服务：

资源简介：

Oxidative stress can lead to plant growth retardation, yield loss, and death. The atr7 mutant of Arabidopsis thaliana exhibits pronounced tolerance to oxidative stress. Using positional cloning, confirmed by knockout and RNA interference (RNAi) lines, we identified the atr7 mutation and revealed that ATR7 is a previously uncharacterized gene with orthologs in other seed plants but with no homology to genes in lower plants, fungi or animals. Expression of ATR7-GFP fusion shows that ATR7 is a nuclear-localized protein. RNA-seq analysis reveals that transcript levels of genes encoding abiotic- and oxidative stress-related transcription factors (DREB19, HSFA2, ZAT10), chromatin remodelers (CHR34), and unknown or uncharacterized proteins (AT5G59390, AT1G30170, AT1G21520) are elevated in atr7. This indicates that atr7 is primed for an upcoming oxidative stress via pathways involving genes of unknown functions. Collectively, the data reveal ATR7 as a novel seed plants-specific nuclear regulator of oxidative stress response.

提供机构：

Benina Maria; Department of Molecular Pharmacology, University of Groningen, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands; Department of Plant Breeding & Genetics, Faculty of Agricultural Sciences & Technology, Bahauddin Zakariya University, Bosan Road, Multan, 60800, Punjab, Pakistan; Fischer Axel; Obata Toshihiro; Gupta Saurabh; Center of Plant Systems Biology and Biotechnology, 139 Ruski Blvd, 4000, Plovdiv, Bulgaria; Max Planck Institute of Molecular Plant Physiology, Am Mühlenberg 1, 14476, Potsdam-Golm, Germany; Balazadeh Salma; Staykov Nikola; Max Planck Institute of Molecular Plant Physiology, Am Mühlenberg 1, 14476, Potsdam-Golm, Germany; Center of Plant Systems Biology and Biotechnology, 139 Ruski Blvd, 4000, Plovdiv, Bulgaria; Department of Plant Physiology and Molecular Biology, University of Plovdiv, 24 Tsar Assen Str, 4000, Plovdiv, Bulgaria; Proost Sebastian; Sujeeth Neerakkal; Omidbakhshfard M. Amin; Mehterov Nikolay; Mueller-Roeber Bernd

创建时间：

2020-12-21