Cu(II)-Catalyzed Intermolecular Amidation of <i>C</i>-Acylimine: A Convenient Access to <i>gem</i>-Diamino Acid Derivatives
收藏NIAID Data Ecosystem2026-03-07 收录
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C-Acylimines 1 undergo intermolecular amidation with amides 2 to produce monoacyl gem-diamino acid derivatives 3 upon treatment with Cu(OTf)2 (20 mol %)/ PPh3 (20 mol %) under mild conditions. This method provides an efficient access to gem-diamino acid equivalents with good to excellent yields.
创建时间：
2016-02-22
