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Single-walled vs. Multi-walled Carbon Nanotubes: Influence of Physico-Chemical Properties on Toxicogenomics Responses in Mouse Lungs

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE223520
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Transcriptional profiling of mouse lung tissue comparing control vs exposure to different carbon nanotubes. The aim was to determine if the physico-chemical properties influence the genotoxic, inflammatory and pro-fibrotic responses. Purified and extracted RNA from lung tissue of female mice C57BL/6J BomTac aged 6-7 weeks exposed for 24 hours to different single-walled carbon nanotubes (SWCNTs) or multi-walled carbon nanotubes (MWCNTs) by single intratracheal instillation of 6, 18 or 54 μg/mouse. n= 8 control group, n=5 each dose group.
创建时间:
2023-04-04
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