The ease of generating genetically modified animals and cell lines has been markedly increased by the recent development of the versatile CRISPR/Cas9 tool. However, while the isolation of isogenic cel
As soybean is an extremely photoperiod-sensitive and self-pollinated crop which lacks any functionally confirmed male sterility genes, the scope of genetic diversity that soybean breeders have harness
Background: Genome-wide association studies (GWAS) have reported hundreds of genomic loci associated with schizophrenia, yet identifying the functional risk variations is a key step in elucidating the
We have developed a CRISPR/Cas9 platform for the analysis of DNA repair outcomes in mouse ES cells. This is a pilot experiment aimed to verify that our current protocol can be scaled up effectively, f