Using tiling arrays to precisely detect DNA targets of THO in yeast

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Crosslinked DNA from wild type cells or from mutant of the THO complex was analyzed by tiling arrays to precisely detect DNA targets of THO in yeast.

采用平铺式微阵列（tiling arrays）对野生型细胞或THO复合物（THO complex）突变体中的交联DNA进行分析，以此精准检测酵母中THO的DNA靶标。