Amino acid substitutions in the transpeptidase domain of PBP3 identified in 95 NTHi isolates.

[24]; the miscellaneous group was classified according to the criteria of García-Cobos et al. [10] and the data from this study.a The isolates were classified into groups I, IIa, IIb and IIc, according to the criteria of Dabernat et al. ≤1 mg/L; AMC Resistant: ≥8/4 mg/L; AMC susceptible: ≤4/2 mg/L;b AMP Resistant: >4 mg/L; AMP Intermediate: 2 mg/L; AMP Susceptible +: positive; -: negative);c BL: Beta-lactamase production ( = 3), ST36, ST98, ST103, ST139 (n = 2), ST145 (n = 3), ST159 (n = 3), ST183, ST203 (n = 3), ST241 (n = 2), ST245, ST266, ST270, ST272, ST385, ST408, ST414 (n = 2), ST519 (n = 4), ST582, ST679, ST714, ST974, ST989, ST990, ST992, ST995, ST1174, ST1176, ST1178, ST1179, ST1180, ST1181, ST1182, ST1183 and ST1184.d ST11 (n