EGFR1 signaling pathway
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The androgen receptor is a member of the nuclear receptor family of ligand activated transcription factors. These receptors bind to steroid hormones, thyroid hormone, retinoids and vitamin D among others, dimerize and bind to DNA. Its ligands include testosterone, dehydroepiandrosterone and androstenedione. Stimulation of the receptor activates the SMAD signaling module. Source: http://www.netpath.org/pathways?path_id=NetPath_4
雄激素受体属于核受体家族中的配体激活转录因子。此类受体与类固醇激素、甲状腺激素、视黄醇和维生素D等物质结合，形成二聚体并绑定至DNA。其配体包括睾酮、脱氢表雄酮和雄烯二酮。受体的激活可启动SMAD信号模块。资料来源：http://www.netpath.org/pathways?path_id=NetPath_4
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