Effect of glycolipids with therapeutic potential on phase behaviour of model ...

B2FIND2026-04-25 收录

细胞膜生物物理

糖尿病免疫调节

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https://b2find.eudat.eu/dataset/83c31050-4765-5867-b1f1-f1b28733ea7e 数据链接链接失效反馈

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alpha-galactosylceramide (a-GalCer) can activate an immune response through a protein-mediated cell signalling event. The effect of a-GalCer on local membrane structure is...

Transcription and splicing regulation by NLRC5 shape the interferon response in human pancreatic β-cells [iPSC scRNAseq]. Transcription and splicing regulation by NLRC5 shape the interferon response in human pancreatic β-cells [iPSC scRNAseq]

糖尿病免疫调节

β细胞单细胞转录组学

IFNa is a key regulator of the dialogue between pancreatic β-cells and the immune system in early type 1 diabetes (T1D). IFNa up-regulates HLA class I expression in human β-cells fostering autoantigen

NIAID Data Ecosystem60

miRNA142-3p targets Tet2 and impairs Treg differentiation and stability in models of type 1 diabetes. miRNA142-3p targets Tet2 and impairs Treg differentiation and stability in models of type 1 diabetes

糖尿病免疫调节

Treg细胞分化与稳定性

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem40

Figure S1 - Simplexide Induces CD1d-Dependent Cytokine and Chemokine Production from Human Monocytes

糖尿病免疫调节

化学合成方法

Reagents and conditions for preparation of synthetic simplexide. a. oxalyl chloride, DMSO, DCM, then Et3N; b. Mg, Et2O; c. Et2O; d. BnBr, NaH, DMF; e. AcOH, HCl; f. CCl3CN, Cs2CO3, DCM; g. PhCH(OCH3)2

Figshare2015-12-02 更新20

DataSheet1_Water-soluble trehalose glycolipids show superior Mincle binding and signaling but impaired phagocytosis and IL-1β production.PDF

疫苗佐剂开发

糖尿病免疫调节

The tremendous potential of trehalose glycolipids as vaccine adjuvants has incentivized the study of how the structures of these ligands relate to their Mincle-mediated agonist activities. Despite thi

NIAID Data Ecosystem50

DataSheet_1_High Serum Vitamin D Concentrations, Induced via Diet, Trigger Immune and Intestinal Microbiota Alterations Leading to Type 1 Diabetes Protection in NOD Mice.pdf

糖尿病免疫调节

肠道微生物组与免疫

The hormonally-active form of vitamin D, 1,25-dihydroxyvitamin D3, can modulate both innate and adaptive immunity, through binding to the nuclear vitamin D receptor expressed in most immune cells. A h

NIAID Data Ecosystem30

Effect of glycolipids with therapeutic potential on phase behaviour of model ...

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