Pilocytic astrocytomas (PA) are the most common brain tumor in pediatric patients and can cause significant morbidity, including chronic neurological deficiencies. They are characterized by activating

NIAID Data Ecosystem60

Genome-wide maps of KDM5A/JARID1A/RBP2 and JARID2/JMJ in HL-1 cardiomyocytes.. Mus musculus

心肌病表观遗传学

发育基因调控

We report the identification of genomic regions bound by RBP2 and JARID2 in mouse cardiomyocytes. RBP2 generates methylated lysine 4 in histone H3. Consistent with previous data, RBP2 binds at the TSS

NIAID Data Ecosystem30

Chromatin structure dynamics of hoxa13a, hoxa13b and hoxd13a loci during zebrafish development.

染色质构象

发育基因调控

We designed 4C-Seq experiments for hoxa13a, hoxa13b and hoxd13a promoters in three developmental stages in zebrafish embryos: 24, 48 and 60 hpf. 4C-seq samples for three different hox13 genes promoter

NIAID Data Ecosystem60

Transcription profiling of Smarce1- MD (R42A) and Smarce1- MD mouse embryonic body

转录组学分析

发育基因调控

To evaluate the differential potential affected by SMARCE1 -MD/MD(R42A) , we performed RNA-sequencing (RNA-seq) of Smarce1-MD and control Smarce1-MD (R42A) embrynoic body. Overall design: we performed

NIAID Data Ecosystem30

Gene expression changes in Dhcr7 knockout brain, lung and liver at E18.5 compared to wild-type embryos

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