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A Cas9 orthologue-mediated cytosine and adenine base editors recognizing NNAAAA PAM sequences
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创建时间:
2022-10-18
相关数据集
Increase base editing efficiency and product variety through fusion of Cas9 nickase to cytosine and adenosine deaminases
Base editors, which are created through fusion of Cas9 nickase to either cytidine or adenine deaminase, efficiently catalyze site-specific nucleotide conversions with minimal indel rates1, 2. However,
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Programmable RNA base editing with a single engineered protein
Programmable base editing of RNA enables rewriting the genetic codes on specific sites. Current tools for specific RNA editing dependent on the assembly or recruitment of the guide RNA into an RNA/pro
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Transient expression of an adenine base editor corrects the Hutchinson-Gilford progeria syndrome mutation and improves the skin phenotype in mice
High-throughput sequencing data of genomic DNA samples from human cells and mouse
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Additional file 4 of PAM-repeat associations and spacer selection preferences in single and co-occurring CRISPR-Cas systems
Additional file 4. CSV containing genomes for which compatible arrays were found with following columns: accession number genome, compatible subtypes of array, PAM, category.
Figshare2021-10-01 更新40
Programmable RNA base editing with a single engineered protein. Programmable RNA base editing with a single engineered protein
Programmable base editing of RNA enables rewriting the genetic codes on specific sites. Current tools for specific RNA editing dependent on the assembly or recruitment of the guide RNA into an RNA/pro
NIAID Data Ecosystem30



