Energy expenditure (EE) and respiratory exchange ratio (RER) were measured over 24 hours by indirect calorimetry in individually housed f/f and KO mice after 20 weeks on HFD (n = 4). Values for EE (kc

NIAID Data Ecosystem60

The Phagocytosis and Toxicity of Amorphous Silica

硅颗粒毒性

细胞吞噬作用

BackgroundInhalation of crystalline silica is known to cause an inflammatory reaction and chronic exposure leads to lung fibrosis and can progress into the disease, silicosis. Cultured macrophages bin

NIAID Data Ecosystem40

Kidney Intercalated Cells Phagocytose and Acidify Escherichia coli

肾脏先天免疫

细胞吞噬作用

Intercalated cells are known to be involved in acid-base homeostasis via vacuolar ATPase (H+-ATPase or V-ATPase) expression. Increasing evidence supports an innate immune role for ICs along with their

NIAID Data Ecosystem90

Tumor-associated macrophages derived from circulating inflammatory monocytes degrade collagen through cellular uptake. Tumor-associated macrophages derived from circulating inflammatory monocytes degrade collagen through cellular uptake

肿瘤微环境重构

细胞吞噬作用

Physiologic turnover of interstitial collagen is mediated by a sequential pathway, in which collagen is fragmented by pericellular collagenases, endocytosed by specific collagen receptors, and routed

NIAID Data Ecosystem50

Red blood cells from mice on high fat diet induce macrophage activation during phagocytosis

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