Extensive Drug Resistance Acquired During Therapy of a Multidrug-resistant Tuberculosis in a High-Income Setting. Acquired Extensive Drug Resistance in Tuberculosis

This study describes the case of a patient with multi-drug resistant tuberculosis (MDR-TB) that developed extensively drug resistant TB (XDR-TB) with additional resistance to two new drugs. Six Mycobacterium tuberculosis isolates were subjected to whole genome sequencing.