Study of the splicing in Thumpd2 knockout mice
收藏NIAID Data Ecosystem2026-05-02 收录
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Splicing is an important step in the maturation of most eukaryotic RNAs. In this work, we studied the effect of m2G72 modification in U6 snRNA on splicing in mouse liver. We performed high-throughput polyA+ RNA sequencing of liver samples from wild-type and Thumpd2 knockout mice. Thumpd2 is methyltransferase catalyzing the indicated N2-methylation of U6 snRNA. Three biological replicates were made for each type of mouse.
创建时间：
2024-05-23
