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Molecular characterization of a region of DNA associated with mutations at the agouti locus in the mouse.

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PubMed Central1991-09-15 更新2026-05-16 收录
下载链接:
https://pmc.ncbi.nlm.nih.gov/articles/PMC52446/
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资源简介:
Molecular characterization of a radiation-induced agouti (a)-locus mutation has resulted in the isolation of a segment of DNA that maps at or near the a locus on chromosome 2 in the mouse. This region of DNA is deleted in several radiation- or chemical-induced homozygous-lethal a-locus mutations and is associated with specific DNA structural alterations in two viable a-locus mutations. We propose that DNA probes from this region of chromosome 2 will be useful for ultimately characterizing the individual gene or genes associated with a-locus function. IMAGES:
提供机构:
National Academy of Sciences
创建时间:
1991-09-15
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