Transcriptome analysis of NSD2/WHSC1/MMSET-depleted human fibroblast cells. Transcriptome analysis of NSD2/WHSC1/MMSET-depleted human fibroblast cells

Transcriptome analysis of NSD2/WHSC1/MMSET-depleted human fibroblast cells revealed that loss of NSD2 downregulates the expression of cell cycle-related genes. Overall design: We depleted NSD2 in IMR-90 human fibroblast cells using three different siRNAs, and then carried out an mRNA-seq analysis.