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Relaxational and diffusive properties of oligomeric and fibrillar forms of al...

B2FIND2026-04-25 收录

蛋白质聚集动力学

神经退行性机制

数据链接：

https://b2find.eudat.eu/dataset/45076b41-b43a-5207-8afd-f38729d67b20 数据链接链接失效反馈

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Neurodegenerative diseases are commonly associated with the accumulation of intracellular or extracellular protein aggregates and are characterized by the misfolding of a...

应用场景：

神经退行性机制

细胞应激通路

Ribosome stalling during translation has recently been shown to cause neurodegeneration, yet the signaling pathways triggered by stalled elongation complexes are unknown. To investigate these pathw

NIAID Data Ecosystem100

Loss of TREM2 reduces hyperactivation of progranulin deficient microglia but not lysosomal pathology [14 months]

神经退行性机制

胶质细胞功能研究

GRN haploinsufficiency causes frontotemporal lobar degeneration and results in microglial hyperactivation, lysosomal dysfunction and TDP-43 deposition. To understand the contribution of microglial hyp

NIAID Data Ecosystem30

Peripheral nerve injury mediated by JEV strain NX1889 infection and impairment of Schwann cells

神经退行性机制

病毒性神经损伤

The original data supporting data for the manuscript:Liping Yang, Yanping Yuan, Qikai Yin, Xiaocong Li, Xue Kang, Qianqian Cui, et al. Peripheral nerve injury mediated by JEV strain NX1889 infection a

Figshare2025-08-15 更新20

AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons. AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons

神经退行性机制

功能障碍研究

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem40

Senataxin, the helicase mutated in AOA2 and ALS4, plays a role in autophagy regulation [HTS]

神经退行性机制

自噬调控通路

Senataxin (SETX) is an RNA/DNA helicase that has been implicated in transcriptional regulation and the DNA damage response, through resolution of R-loop structures. Mutations in SETX result in either

NIAID Data Ecosystem20

Relaxational and diffusive properties of oligomeric and fibrillar forms of al...

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