Crystal Structure of VIM-2 metallo-beta-lactamase in complex with ML302F
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Crystal Structure of VIM-2 metallo-beta-lactamase in complex with ML302F Descriptor: (2Z)-2-sulfanyl-3-(2,3,6-trichlorophenyl)prop-2-enoic acid, Beta-lactamase class B VIM-2, FORMIC ACID, ... Authors: Aik, W.S, Brem, J, McDonough, M.A, Schofield, C.J. Deposit date: 2014-03-18 Release date: 2014-11-19 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Rhodanine hydrolysis leads to potent thioenolate mediated metallo-beta-lactamase inhibition. Nat.Chem., 6, 2014
VIM-2金属β-内酰胺酶与ML302F结合复合物的晶体结构
配体描述:(2Z)-2-巯基-3-(2,3,6-三氯苯基)丙-2-烯酸、B类β-内酰胺酶VIM-2、甲酸……
作者:Aik W.S.、Brem J.、McDonough M.A.、Schofield C.J.
提交日期:2014-03-18
发布日期:2014-11-19
最后修改日期:2023-11-08
实验方法:X射线衍射(分辨率2 Å)
引用文献:若丹宁水解可产生硫代烯醇盐介导的强效金属β-内酰胺酶抑制作用,《Nature Chemistry》,6卷,2014年
创建时间:
2014-03-18



