MAP4K4 in complex with inhibitor (compound 22), 6-(3-CHLOROPHENYL)QUINAZOLIN-4-AMINE

Protein Data Bank Japan2024-02-28 更新2026-03-21 收录

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MAP4K4 in complex with inhibitor (compound 22), 6-(3-CHLOROPHENYL)QUINAZOLIN-4-AMINE Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-(3-chlorophenyl)quinazolin-4-amine, Mitogen-activated protein kinase kinase kinase kinase 4, ... Authors: Harris, S.F, Wu, P, Coons, M. Deposit date: 2014-01-07 Release date: 2014-04-23 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Discovery of Selective 4-Amino-pyridopyrimidine Inhibitors of MAP4K4 Using Fragment-Based Lead Identification and Optimization. J.Med.Chem., 57, 2014

MAP4K4与抑制剂（化合物22，6-(3-氯苯基)喹唑啉-4-胺）的复合物。描述符：2-(N-吗啉代)乙磺酸、6-(3-氯苯基)喹唑啉-4-胺、丝裂原活化蛋白激酶激酶激酶激酶4（MAP4K4）…… 作者：Harris, S.F.、Wu, P、Coons, M. 提交日期：2014-01-07 发布日期：2014-04-23 最后修改日期：2024-02-28 实验方法：X射线衍射（分辨率2.1 Å）引用文献：《Discovery of Selective 4-Amino-pyridopyrimidine Inhibitors of MAP4K4 Using Fragment-Based Lead Identification and Optimization》，《药物化学杂志》（Journal of Medicinal Chemistry），2014年，第57卷

创建时间：

2014-01-07