Profiling pancreatic islets from obese db/db and lean control db/+ mice

ChEBI2013-03-22 更新2026-07-21 收录

糖尿病模型

胰腺组织分析

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-31953 数据链接链接失效反馈

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Profiling pancreatic islets from obese db/db and lean control db/+ mice

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2013-03-22

β-cell adaptation in mice expressing exclusively lamin C counteracts glucose intolerance associated with aging, obesity and diabetes (LamineA-C_RRBS). β-cell adaptation in mice expressing exclusively lamin C counteracts glucose intolerance associated with aging, obesity and diabetes (LamineA-C_RRBS)

β细胞功能与代谢适应

糖尿病模型

Lamin A, lamin C and progerin, produced by alternative RNA processing of LMNA gene, are intermediate filaments involved in nuclear and chromatin architecture. We investigate the ability of LMNALCS/LCS

NIAID Data Ecosystem120

Simultaneous SGLT2 Inhibition and Caloric Restriction Improves Insulin Resistance and Kidney Function in OLETF Rats (Data)

糖尿病模型

代谢组学分析

Metabolomics dataset1) Raw data2) Transformed data3) p-values and FDR by comparison

Figshare2021-04-13 更新40

Mus musculus Genome sequencing. Mus musculus

糖尿病模型

器官转录组学

Renal transcriptomics in db/db mice

NIAID Data Ecosystem10

Histone ChIP-seq from pancreas (ENCSR703XCI)

表观遗传学

胰腺组织分析

H3K9me3 ChIP-seq on pancreas tissue female adult (61 years) For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_

NIAID Data Ecosystem40

Sarpogrelate hydrochloride ameliorates diabetic nephropathy associated with inhibition of macrophage activity and inflammatory reaction in db/db mice

糖尿病模型

药物疗效评估

The aim of this study was to evaluate the effects of sarpogrelate hydrochloride (SH), a selective serotonin 2A receptor antagonist, on diabetic nephropathy in a type 2 diabetes mouse model. We treated

Figshare2017-06-23 更新30

Profiling pancreatic islets from obese db/db and lean control db/+ mice

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