Additional file 3 of Tissue of origin detection for cancer tumor using low-depth cfDNA samples through combination of tumor-specific methylation atlas and genome-wide methylation density in graph convolutional neural networks
We first identified candidate VMRs, defined as regions of CpG-sites showing the highest variability across all methylation sites.To examine the factors that best explain the variance in methylation in
Density-Flow.dat and Density-Velocity.dat are the raw data in Fig. 3 Syn-flow.dat and Syn-density.dat are the raw data in Fig. 4 Meandist.dat, Steplength.dat and Safedist are the raw data in Fig. 5 Sy