IL18

ENCODES a protein that exhibits cytokine activity; interleukin-18 receptor binding (ortholog); INVOLVED IN extrinsic apoptotic signaling pathway via death domain receptors; positive regulation of cell population proliferation; positive regulation of type II interferon production; PARTICIPATES IN interleukin-12 signaling pathway; interleukin-23 signaling pathway; interleukin-27 signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Acute Lung Injury (ortholog); alcoholic hepatitis (ortholog); FOUND IN apical plasma membrane (ortholog); extracellular space (ortholog); INTERACTS WITH Belnacasan; cadmium atom; cadmium dichloride

编码一种表现出细胞因子活性的蛋白质；白细胞介素-18受体结合（同源）；通过死亡结构域受体参与外源性细胞凋亡信号通路；调控细胞增殖；正向调控II型干扰素的产生；参与白细胞介素-12信号通路；参与白细胞介素-23信号通路；参与白细胞介素-27信号通路；与急性肾衰竭（同源）相关；与急性肺损伤（同源）；与酒精性肝炎（同源）；存在于顶膜（同源）；存在于细胞外空间（同源）；与贝那卡桑；镉原子；氯化镉相互作用。